Short-Term Prognostic Model for Non-Traumatic Intracerebral Hemorrhage Patients: A Combination of Four Score, FUNC Score, and ICH Score

Nurvira Annisa Saragih; Alfansuri Kadri; Chairil Amin Batubara

doi:10.47353/jsocmed.v3i1.114

Short-Term Prognostic Model for Non-Traumatic Intracerebral Hemorrhage Patients: A Combination of Four Score, FUNC Score, and ICH Score

Nurvira Annisa Saragih
Resident of Neurology Department, Faculty of Medicine, Universitas Sumatera Utara/ H. Adam Malik Hospital, Medan, Indonesia
Alfansuri Kadri
Staff of Neurology Department, Faculty of Medicine, Universitas Sumatera Utara/ H. Adam Malik Hospital, Medan, Indonesia
Chairil Amin Batubara
Staff of Neurology Department, Faculty of Medicine, Universitas Sumatera Utara/ H. Adam Malik Hospital, Medan, Indonesia

Abstract

Introduction: Currently, the Functional Outcome in Patients With Primary Intracerebral Hemorrhage (FUNC) score, Full Outline of UnResponsiveness (FOUR) score, and Intracerebral Hemorrhage (ICH) score are utilized to predict outcomes in non-traumatic intracerebral hemorrhage (ICH) patients. The high mortality rate in non-traumatic ICH patients emphasizes the importance of scoring systems as predictive models for mortality prognosis. The aim of this study was to determine a short-term prognostic model for non-traumatic ICH patients by combining FUNC score, FOUR score, and ICH score.

Method: This observational cohort study took place at the neurology ward and Intensive Care Unit of RSUP H. Adam Malik – Medan, from March to September 2023. Subjects meeting the study criteria were observed for 30 days to assess short-term outcomes (mortality). Multivariate logistic regression analysis was then conducted for the combined scores.

Results: Significant effects were found between FUNC score, FOUR score, and ICH score on short-term mortality in non-traumatic ICH patients, each with a p-value < 0.001. However, the multivariate logistic regression analysis yielded statistically non-significant results (p > 0.05).

Conclusion: While FUNC, FOUR, and ICH scores individually show a significant correlation with short-term mortality in non-traumatic ICH patients, their combination is ineffective for predicting mortality in this group.

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Published at

29. January 2024
https://doi.org/10.47353/jsocmed.v3i1.114
Issue:

Vol. 3 No. 1 (2024): January
Section:

Articles
Keywords:

FUNC score FOUR score ICH score Short-term mortality Non-traumatic Intracerebral hemorrhage
References:

Dekker SE, Hoffer SA, Selman W, Bambakidis NC. Spontaneous Intracerebral Hemorrhage. In: Principles of Neurological Surgery. Elsevier Inc.; 2018. p. 334-342.e2.

Elliott J, Smith M. The acute management of intracerebral hemorrhage: a clinical review. Anesth Analg. 2010;110(5):1419-27. Doi: 10.1213/ANE.0b013e3181d568c8

Greenberg S. Handbook of Neurosurgery. Vol. 9. 2020. p. 1402–1420

Greenberg SM, Ziai WC, Cordonnier C, Dowlatshahi D, Francis B, Goldstein JN, et al. 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association. Stroke. 2022; 53 (7): e282-e361. doi: 10.1161/STR.0000000000000407.

Hostettler IC, Seiffge DJ, Werring DJ. Intracerebral hemorrhage: an update on diagnosis and treatment. Expert Rev Neurother. 2019; 19 (7): 679-694.

Amer HA, El-Jaafary SIM, Sadek HMAE, Fouad AM, Mohammed SS. Clinical and paraclinical predictors of early neurological deterioration and poor outcome in spontaneous intracerebral hemorrhage. Egypt J Neurol Psychiatr Neurosurg. 2023; 59 (1): 74.

Godoy DA, Piñero G, Di Napoli M. Predicting mortality in spontaneous intracerebral hemorrhage: can modification to original score improve the prediction? Stroke. 2006; 37 (4): 1038-44.

Hadi KH, Sheaheed NM, Karim AK, Rasheed JI. Prognostic Value of Intracerebral Hemorrhage Score in Patients with Spontaneous Intracerebral Hemorrhage. Iraq Med J. 2019; 3 (1).

Sahni R, Weinberger J. Management of intracerebral hemorrhage. Vasc Health Risk Manag. 2007; 3 (5): 701-9.

Garrett JS, Zarghouni M, Layton KF, Graybeal D, Daoud YA. Validation of clinical prediction scores in patients with primary intracerebral hemorrhage. Neurocrit Care. 2013; 19 (3): 329-35.

Rost NS, Smith EE, Chang Y, Snider RW, Chanderraj R, Schwab K, FitzMaurice E, Wendell L, Goldstein JN, Greenberg SM, Rosand J. Prediction of functional outcome in patients with primary intracerebral hemorrhage: the FUNC score. Stroke. 2008; 39 (8): 2304-9.

Mittal MK, Lele A. Predictors of poor outcome at hospital discharge following a spontaneous intracerebral hemorrhage. Int J Neurosci. 2011; 121 (5): 267-70.

Safatli DA, Günther A, Schlattmann P, Schwarz F, Kalff R, Ewald C. Predictors of 30-day mortality in patients with spontaneous primary intracerebral hemorrhage. Surg Neurol Int. 2016; 7 (Suppl 18): S510-7.

Lun R, Yogendrakumar V, Ramsay T, Shamy M, Fahed R, Selim MH, Dowlatshahi D. Predicting long-term outcomes in acute intracerebral haemorrhage using delayed prognostication scores. Stroke Vasc Neurol. 2021; 6 (4): 536-541.

Fernando SM, Qureshi D, Talarico R, Tanuseputro P, Dowlatshahi D, Sood MM, Smith EE, Hill MD, McCredie VA, Scales DC, English SW, Rochwerg B, Kyeremanteng K. Intracerebral Hemorrhage Incidence, Mortality, and Association With Oral Anticoagulation Use: A Population Study. Stroke. 2021; 52 (5): 1673-1681.

An SJ, Kim TJ, Yoon BW. Epidemiology, Risk Factors, and Clinical Features of Intracerebral Hemorrhage: An Update. J Stroke. 2017; 19 (1): 3-10.

Hemphill JC 3rd, Bonovich DC, Besmertis L, Manley GT, Johnston SC. The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke. 2001; 32 (4): 891-7.

Braksick SA, Hemphill JC 3rd, Mandrekar J, Wijdicks EFM, Fugate JE. Application of the FOUR Score in Intracerebral Hemorrhage Risk Analysis. J Stroke Cerebrovasc Dis. 2018; 27 (6): 1565-1569.

Lim MJR, Neo AYY, Singh GD, Liew YST, Rajendram MF, Tan MWX, Ragupathi T, Lwin S, Chou N, Sharma VK, Yeo TT. The Evaluation of Prognostic Scores in Spontaneous Intracerebral Hemorrhage in an Asian Population: A Retrospective Study. J Stroke Cerebrovasc Dis. 2020; 29 (12): 105360.

Sitohang S, Sabri. The Relationship of ICH Score and 30-Day Mortality Rate in Hemorrhagic Stroke Patient: Systematic Review and Meta-Analysis. Sumat Med J. 2021; 4 (2).

Rahmani F, Rikhtegar R, Ala A, Farkhad-Rasooli A, Ebrahimi-Bakhtavar H. Predicting 30-day mortality in patients with primary intracerebral hemorrhage: Evaluation of the value of intracerebral hemorrhage and modified new intracerebral hemorrhage scores. Iran J Neurol. 2018; 17 (1): 47-52.

Faghih-Jouybari M, Raof MT, Abdollahzade S, Jamshidi S, Padegane T, Ehteshami S, Fateh S. Mortality and morbidity in patients with spontaneous intracerebral hemorrhage: A single-center experience. Curr J Neurol. 2021; 20 (1): 32-36.

Masotti L, Lorenzini G, Di Napoli M, Godoy DA. Prognostic ability of four clinical grading scores in spontaneous intracerebral hemorrhage. Acta Neurol Belg. 2017; 117 (1): 325-327.
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Saragih, N. A., Alfansuri Kadri, & Chairil Amin Batubara. (2024). Short-Term Prognostic Model for Non-Traumatic Intracerebral Hemorrhage Patients: A Combination of Four Score, FUNC Score, and ICH Score. Journal of Society Medicine, 3(1), 6–14. https://doi.org/10.47353/jsocmed.v3i1.114