Differences in MPV (Mean Platelet Volume) / Lymphocytes Ratio In Chronic Hepatitis B with and without Cirrhosis Hepatic
Authors
Abstract
Introduction: The MPV/Lymphocyte Ratio is a simple inflammatory parameter that can be obtained from a complete blood count. Hepatitis patients with liver cirrhosis have a higher MPV causing thrombopoietin to decrease so that the platelet count decreases. The inflammatory response can cause a decrease in the number of lymphocytes and is closely related to a poor prognosis in patients with hepatitis B virus. This study aims to examine the differences in the MPV/Lymphocyte ratio in chronic hepatitis B patients with and without liver cirrhosis.
Methods: The samples for this study was chronic hepatitis B patients with and without liver cirrhosis who met he inclusion criteria. The research was carried out by taking blood samples from 94 patients treated in the internal medicine treatment room and Gastroenterohepatology polyclinic at Adam Malik Hospital, Medan. Samples were examined for MPV, absolute lymphocytes, then the MPV/lymphocyte ratio was calculated.
Results: The total number of subjects in this study was 94 and there were 62 men and 32 women. The results of the analysis showed that there was a significant difference between the cirrhotic and non-cirrhotic groups (p = 0.001).
Conclusion: There was a significant difference in the ratio of MPV/lymphocytes in the group of hepatitis B subjects with cirrhosis and in the group of hepatitis B subjects without liver cirrhosis. (p = 0.001).
Similar Articles
- Olivia Monica Deneuve, Andika Pradana, Amira P Tarigan, The Relationship Between ICS LABA Administration and Blood Eosinophil Levels in COPD Patient at USU General Hospital , Journal of Society Medicine: Vol. 3 No. 12 (2024): December
- Azwar Iwan Tona , Pharmacologic Management of Hypertensive Disorders of Pregnancy and Postpartum Hypertension: Current Evidence and Clinical Implications , Journal of Society Medicine: Vol. 5 No. 2 (2026): February
- Muhammad Bayhaqi Dalimunthe, Andika Pradana, Amira Permatasari Tarigan, Rina Amelia, The Relationship between Malnutrition and Quality of Life in Stable Chronic Obstructive Pulmonary Disease Patients at Prof. Dr. Chairuddin P. Lubis Hospital Field , Journal of Society Medicine: Vol. 3 No. 9 (2024): September
- Jessica Patricia Pangaribuan, Santi Syafril, Dian Anindita Lubis, Rahmad Isnanta, Imelda Rey, Effect of Glycemic Parameters on Mortality of Type 2 Diabetes Mellitus Patients with COVID-19 Infection in Haji Adam Malik Hospital Medan , Journal of Society Medicine: Vol. 2 No. 8 (2023): August
- Rendi Sidiq, Bastian Lubis, Yutu Solihat, Comparison of Pre-Loading Fluid With Norepinephrine Toward Mean Arterial Pressure (MAP) In Sepsis Patients In Intensive Care Unit (ICU) of Haji Adam Malik General Hospital, Medan , Journal of Society Medicine: Vol. 1 No. 2 (2022): November
- Eka Damayanti , Doddy Tavianto, Postoperative Pulmonary Hypertension After Complete Tetralogy of Fallot Repair: Mechanistic Determinants and Prognostic Implications for Early Clinical Outcomes , Journal of Society Medicine: Vol. 5 No. 3 (2026): March
- Indah Triana Sari Pohan, Amira Permatasari Tarigan, Pandia Pandiaman, Mutiara Erna, The Effect of Providing Digital Education Through Smartphone Applications on Control Level of Asthma Patients at Outpatient Clinic University of North Sumatra Hospital Medan , Journal of Society Medicine: Vol. 4 No. 4 (2025): April
- Mirton, Pasihulilzan, Hesty Rhauda Ashan, Performed Laparoscopic Surgery For Gastric Perforation: Case Report , Journal of Society Medicine: Vol. 3 No. 6 (2024): June
- Nengah Darmawan, Amira Permatasari Tarigan, Andika Pradana, Relationship Between Asthma Therapy Types, Pulmonary Function, and Asthma Control in Primary Healthcare Facilities in Medan , Journal of Society Medicine: Vol. 4 No. 2 (2025): February
- Al-Ma’ Arij Akbar Lubis, Cut Aryfa Andra, Andre Pasha Ketaren, Relationship between QTc interval prolongation and mortality of acute ischaemic stroke patients during treatment and three months after treatment at Adam Malik Hospital , Journal of Society Medicine: Vol. 3 No. 3 (2024): March
You may also start an advanced similarity search for this article.