The Relationship between D-Dimer Levels and Coronary Lesion Severity in Patients with Acute Myocardial Infarction with ST-Segment Elevation at Haji Adam Malik Hospital Medan

M. Isfan Rialdy; Nizam Zikri Akbar; T. Bob Haykal; Andre Pasha Ketaren; Cut Aryfa Andra; Yuke Sarastri

doi:10.47353/jsocmed.v2i9.89

The Relationship between D-Dimer Levels and Coronary Lesion Severity in Patients with Acute Myocardial Infarction with ST-Segment Elevation at Haji Adam Malik Hospital Medan

M. Isfan Rialdy
Cardiology and Vascular Resident, Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia / Haji Adam Malik General Hospital, Medan, Indonesia
Nizam Zikri Akbar
Cardiologist, Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia / Haji Adam Malik General Hospital, Medan, Indonesia
T. Bob Haykal
Cardiologist, Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia / Haji Adam Malik General Hospital, Medan, Indonesia
Andre Pasha Ketaren
Cardiologist, Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia / Haji Adam Malik General Hospital, Medan, Indonesia
Cut Aryfa Andra
Cardiologist, Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia / Haji Adam Malik General Hospital, Medan, Indonesia
Yuke Sarastri
Cardiologist, Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia / Haji Adam Malik General Hospital, Medan, Indonesia

Abstract

Introduction: Acute coronary syndrome results from rupture or erosion of an atherosclerotic plaque. D-dimer is a direct marker of fibronolysis events and an indirect marker of hypercoagulable state associated with atherosclerotic plaque formation and acute coronary syndrome. The purpose of this study was to determine the relationship between D-dimer levels and the severity of coronary lesions in ST Elevation Myocardial Infarction patients at H. Adam Malik Hospital Medan.

Method: This study was conducted with a cross-sectional method on 72 ST Elevation Myocardial Infarction patients at H. Adam Malik Medan Hospital who underwent coronary angiography from December 2022 to May 2023. Definition of ST Elevation Myocardial Infarction followed the definition of Universal Definition of Myocardial Infarction and the severity of coronary lesions was calculated based on syntax score. Data were analyzed univariately and bivariately using SPSS to assess the association of D-dimer levels with syntax score with p<0.05 considered statistically significant.

Results: The total study subjects were 72 people with an average age of 56,5410,84years. Most of the study samples were male 56 people (77.8%). The median D-dimer level was 605 and mean syntax score 22.027 + 14.61. There is a significant relationship between D-dimer levels and the severity of coronary lesions based on the syntax score (p: <0.001).

Conclusion: There is a significant relationship between D-dimer and severity of coronary lesions in patients with acute myocardial infarction with ST segment elevation at H. Adam Malik General Hospital, Medan.

Similar Articles

Radian Ahmad Halimi, Ardi Zulfariansyah, Post-Operative Management for Craniotomy Decompression in Cerebral Edema Patients Due to Cerebral Infarction in The Right Carotic System which Occurred Cerebral Vasospasm , Journal of Society Medicine: Vol. 3 No. 4 (2024): April
Abdurrahman Asysyarif, Elvita Rahmi Daulay, Kiking Ritarwan, Correlation of Lacunar Infarct on Head Ct Scan with Dysarthria in Haji Adam Malik General Hospital in 2019 , Journal of Society Medicine: Vol. 2 No. 1 (2023): January
Ade Sinaga, Tasrif Hamdi, Qadri Fauzi Tanjung, Correlation Analysis of Lemon, IDS, and Wilson Scores in Assessing Intubation Difficulty in Patients Undergoing General Anesthesia , Journal of Society Medicine: Vol. 3 No. 8 (2024): August
Utama Hadiputra Surbakti, R.A. Dwi Pujiastuti, Kiking Ritarwan, Associations between Depression and Anxiety with Sleep Quality in Post Stroke Patients , Journal of Society Medicine: Vol. 2 No. 3 (2023): March
Khansa Salsabila, Puji Pinta Omas Sinurat, Irina Kemala Nasution, Association between Coagulation Profile and Platelet Lymphocyte Ratio with Karnofsky Performance Status Scale In Brain Tumor Patients , Journal of Society Medicine: Vol. 2 No. 5 (2023): May
Defriyan Ramzi, Refli Hasan, Zainal Safri, Relationship between Atherogenic Index of Plasma (AIP) and Mayor Cardiovascular Event (MACE) in Patients with Acute Myocardial Infarction (IMA) with Percutaneous Coronary Intervention (PCI) in Haji Adam Malik Hospital , Journal of Society Medicine: Vol. 3 No. 5 (2024): May
Rahmah Evelin Lubis, Diza Tanzira, Nurhakiki Zahara Arif, Cardiovascular Disease with COVID-19 in Rural Area: Case Series , Journal of Society Medicine: Vol. 2 No. 6 (2023): June
Fadli Ilhami, Ali Nafiah Nasution, Cut Aryfa Andra, Prognostic Value of Tricuspid Annular Plane Systolic Excursion (TAPSE), Right Ventricular Fractional Area Changes (RV FAC) and Pulses Tissue Doppler S' Wave (PTD S') at 30 Days after Care of Acute Miocardial Infarction Patients in Haji Adam Malik Hospital , Journal of Society Medicine: Vol. 2 No. 5 (2023): May
Siti Hasnita Oktavia Purba, Iskandar Nasution, R.A. Dwi Pujiastuti, The Correlation between Dehydration and Early Neurological Deterioration in Acute Hemorrhagic Stroke , Journal of Society Medicine: Vol. 3 No. 1 (2024): January
Marisa Heidiyana, Khairul Putra Surbakti, Haflin Soraya Hutagalung, The Association Between Degree of Severity and Number of Medications with Quality of Life in Parkinson's Disease Patients , Journal of Society Medicine: Vol. 2 No. 4 (2023): April

<< < 1 2 3 4 > >>

You may also start an advanced similarity search for this article.

PDF

Published at

30. September 2023
https://doi.org/10.47353/jsocmed.v2i9.89
Issue:

Vol. 2 No. 9 (2023): September
Section:

Articles
Keywords:

D-dimer ST Elevation Myocardial Infarction SYNTAX score
References:

Biccirè FG, Farcomeni A, Gaudio C, Pignatelli P, Tanzilli G, Pastori D. D-dimer for risk stratification and antithrombotic treatment management in acute coronary syndrome patients: A systematic review and metanalysis. Thrombosis Journal. 2021;19(1):1–14.

Song C, Fu R, Li S, Yang J, Wang Y, Xu H, et al. Simple risk score based on the China Acute Myocardial Infarction Registry for predicting in-hospital mortality among patients with non-st-segment elevation myocardial infarction: Results of a prospective observational cohort study. BMJ Open. 2019;9(9):1–7.

Badan Penelitian dan Pengembangan Kesehatan Kemenkes RI. Riset Kesehatan Dasar 2018. 2019.

Zhao Y, Wang H, Lin Z, Ji Y, Chen Q. Relationship between D-dimer / kreatinine ratio and coronary artery disease severity in patients with st-segment elevation myocardial infarction. 2021:1–10.

Turkoglu C, Harbalıoğlu H, Şeker T, Baykan AO, Uysal OK. D-dimers are associated with coronary artery disease severity assessed using syntax and syntax II scores in patients with st elevation myocardial infarction. Revista Portuguesa de Cardiologia. 2020;39(12):687–93.

Serruys P, Onuma Y, Garg S, Sarno G, van den Brand M, Kappetein A-P, et al. Assessment of the syntax score in the Syntax Study. EuroIntervention. 2009;5(1):50–6.

Yuksel M, Yildiz A, Oylumlu M, Akyuz A, Aydin M, Kaya H, et al. The association between platelet/lymphocyte ratio and coronary artery disease severity. The Anatolian Journal of Cardiology. 2015;15(8):640–7.

Sianos G, Morel MA, Kappetein AP, Morice MC, Colombo A, Dawkins K, Brand MVD.et al. The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease. EuroIntervention. 2005;1(2):219-227.

Saif Mohammed AA, Lin X, Al hashedi E, Sun R, Yu J. Correlation between Hypertension and SYNTAX Score in Patients with Chest Pain Admitted to Cardiology Department for Coronary Angiography. World J Cardiovasc Dis. 2021;11(04):231–41.

Koch V, Booz C, Gruenewald LD, Albrecht MH, Gruber-Rouh T, Eichler K, et al. Diagnostic performance and predictive value of D-dimer testing in patients referred to the Emergency Department for Suspected Myocardial Infarction. Clinical Biochemistry. 2022;104:22–9.
Share:

Z

Rialdy, M. I., Akbar, N. Z., Haykal, T. B., Ketaren, A. P., Andra, C. A., & Sarastri, Y. (2023). The Relationship between D-Dimer Levels and Coronary Lesion Severity in Patients with Acute Myocardial Infarction with ST-Segment Elevation at Haji Adam Malik Hospital Medan. Journal of Society Medicine, 2(9), 314–320. https://doi.org/10.47353/jsocmed.v2i9.89