Serum Procalcitonin (PCT) Level In Acute Kidney Injury (AKI) In Critical Patients
Acute Kidney Injury (AKI) In Critical Patients
Authors
Abstract
Early prediction and avoidance of aggravation of AKI will be useful in identifying patients at risk of developing a higher degree of AKI. Many studies have been conducted to prevent AKI and find biomarkers to predict AKI. Many studies have identified biomarkers of AKI, such as neutrophil-associated lipocalin (NGAL), cystatin C, interleukin-18, and tissue inhibitors of metalloproteinase-2 (TIMP-2). Yet few have investigated the role of PCT as a predictor of AKI. The pathophysiological mechanisms that explain the association between serum PCT and AKI remain unclear. Various inflammatory responses are thought to play a role in the AKI development. PCT acts as a chemoattractant in the inflammation area and causes more monocytes to invade the inflammation. PCT is initially produced in adherent monocytes and then contributes to an increase in circulating PCT by attracting parenchymal cells as they attach directly to activated monocytes. High PCT levels ultimately act as a direct chemoattractant to monocyte counts.
Similar Articles
- Bastian Lubis, Putri Amelia, Muhammad Akil, Vincent Viandy, Ade Winata, Yohanes WH George, Early Continuous Renal Replacement Therapy In Patients With St-Elevation Myocardial Infarction And Covid-19 After Percutaneous Coronary Intervention: A Case Report , Journal of Society Medicine: Vol. 1 No. 2 (2022): November
- Siti Hasnita Oktavia Purba, Iskandar Nasution, R.A. Dwi Pujiastuti, The Correlation between Dehydration and Early Neurological Deterioration in Acute Hemorrhagic Stroke , Journal of Society Medicine: Vol. 3 No. 1 (2024): January
- Rendi Sidiq, Bastian Lubis, Yutu Solihat, Comparison of Pre-Loading Fluid With Norepinephrine Toward Mean Arterial Pressure (MAP) In Sepsis Patients In Intensive Care Unit (ICU) of Haji Adam Malik General Hospital, Medan , Journal of Society Medicine: Vol. 1 No. 2 (2022): November
- Batian Lubis, Dis Bima P Purwaamidjaja, Mayang Indah Lestari, Faisal, Muhammad Husni Thamrin, Febri Akhmad Belinda, A Case Series of Bleeding Complication Post Percutaneous Dilatational Tracheostomy and Management , Journal of Society Medicine: Vol. 2 No. 12 (2023): December
- Muhammad Harmen Reza Siregar, Elvita Rahmi Daulay, Refli Hasan, Role of Chest Radiograph in Diagnosis of Acyanotic Congenital Heart Disease , Journal of Society Medicine: Vol. 1 No. 3 (2022): December
- Artha Wahyu Wardana, Muchammad Erias Erlangga, Management of Guillain-Barré Syndrome with Respiratory Distress in a Pregnant Woman: A Case Report , Journal of Society Medicine: Vol. 3 No. 1 (2024): January
- Diko Hamonangan Saragih, Cut Aria Arina, Iskandar Nasution, The Association Between ASPECTS Score and Dysphagia in Acute Ischemic Stroke Patients , Journal of Society Medicine: Vol. 2 No. 7 (2023): July
- Tasrif Hamdi, What is the function of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in pain processes? , Journal of Society Medicine: Vol. 2 No. 2 (2023): February
- Sharanjit Dhillon, Aida Fithrie, Chairil Amin Batubara, The Association between Waist Hip Ratio and Severity of Diabetic Peripheral Neuropaty in Diabetes Melitus Type 2 by Using Toronto Clinical Scoring System , Journal of Society Medicine: Vol. 2 No. 4 (2023): April
- M. Randy Harry, Elvita Rahmi Daulay, Radar Radius Tarigan, Correlation of Kidney Volume on CT-Scan with Kidney Function Tests in Patients with Normal Kidneys at Haji Adam Malik Hospital Medan in 2020-2021 , Journal of Society Medicine: Vol. 2 No. 4 (2023): April
You may also start an advanced similarity search for this article.