Estimated Glomerular Filtration Rate (eGFR) as a Predictor of 1-Month Clinical Outcome in First-Ever Acute Ischemic Stroke Patients
Authors
Abstract
Introduction: Renal dysfunction is a new risk factor that is thought to influence the clinical outcome of acute ischemic stroke. In this case, the estimated glomerular filtration rate (eGFR) value is used as an approach to assess kidney function status in acute ischemic stroke patients. This study aims to find the relationship between eGFR and clinical outcomes of acute ischemic stroke.
Method: 70 samples were obtained according to inclusion criteria. eGFR is calculated within first week of stroke onset using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula. A normality test was carried out on the data, then determined the correlation and compared eGFR with good [modified Rankin Scale (mRS) 0-2] and poor (mRS 3-6) clinical outcomes on the 30th day.
Results: In this study, the average age of the sample was 61.37 years. The largest population was in the 45-59 mL/min/1.73 m2 eGFR group (38,6%). The mean eGFR (p<0.001) for all samples, good, and bad outcome groups was respectively 59.90 ± 21.09, 79.79 ± 19.21, and 52.49 ± 16.57. In this study the poor outcome group had a lower mean eGFR than the good outcome group (52.49 mL/min/1.73 m2 vs 79.79 mL/min/1.73 m2), with a cut-off value of 62 mL/min/1.73 m2 (sensitivity 80.39%, specificity 84.21%) tended to have worse clinical outcomes.
Conclusion: Based on the results of this study, eGFR has a relationship with clinical outcomes (p<0.001) and can objectively predict clinical outcomes on the 30th day of acute ischemic stroke.
Similar Articles
- Batian Lubis, Dis Bima P Purwaamidjaja, Mayang Indah Lestari, Faisal, Muhammad Husni Thamrin, Febri Akhmad Belinda, A Case Series of Bleeding Complication Post Percutaneous Dilatational Tracheostomy and Management , Journal of Society Medicine: Vol. 2 No. 12 (2023): December
- Robert Sihombing, Osmond Muftilov Pison, Management of Patients with Guillain Barre Syndrome Accompanied by Ventilator Associated Pneumonia , Journal of Society Medicine: Vol. 3 No. 5 (2024): May
- Lastri Hillary, Ali Nafiah Nasution, Anggia Chairuddin Lubis, Correlation of P Wave Dispersion and Quality of Life of Heart Failure Due to Coronary Heart Disease Patient in Haji Adam Malik General Hospital , Journal of Society Medicine: Vol. 3 No. 4 (2024): April
- Bastian Lubis, Putri Amelia, Muhammad Akil, Vincent Viandy, Ade Winata, Yohanes WH George, Early Continuous Renal Replacement Therapy In Patients With St-Elevation Myocardial Infarction And Covid-19 After Percutaneous Coronary Intervention: A Case Report , Journal of Society Medicine: Vol. 1 No. 2 (2022): November
- Khansa Salsabila, Puji Pinta Omas Sinurat, Irina Kemala Nasution, Association between Coagulation Profile and Platelet Lymphocyte Ratio with Karnofsky Performance Status Scale In Brain Tumor Patients , Journal of Society Medicine: Vol. 2 No. 5 (2023): May
- Adityo Prabowo, Use of Chest X-Ray (CXR) in Covid-19 Screening as A Modalities , Journal of Society Medicine: Vol. 1 No. 2 (2022): November
- Jessica Patricia Pangaribuan, Santi Syafril, Dian Anindita Lubis, Rahmad Isnanta, Imelda Rey, Effect of Glycemic Parameters on Mortality of Type 2 Diabetes Mellitus Patients with COVID-19 Infection in Haji Adam Malik Hospital Medan , Journal of Society Medicine: Vol. 2 No. 8 (2023): August
- Cindy Giovanni, Nurita Dian Kestriani Saragi Sitio, Role of Intravenous Immunoglobulin (IVIG) in Patients with Guillain Barre Syndrome with Severe Community Pneumonia in The Intensive Care Unit (ICU) , Journal of Society Medicine: Vol. 3 No. 3 (2024): March
- Radian Ahmad Halimi, Ardi Zulfariansyah, Post-Operative Management for Craniotomy Decompression in Cerebral Edema Patients Due to Cerebral Infarction in The Right Carotic System which Occurred Cerebral Vasospasm , Journal of Society Medicine: Vol. 3 No. 4 (2024): April
- Fakhrur Rozi, Khairul Putra Surbakti, Irina Kemala Nasution, The Relationship between Fatigue and The Incidence of Tension-Type Headache in The First Semester Resident Doctors of The Faculty of Medicine Universitas Sumatera Utara , Journal of Society Medicine: Vol. 2 No. 6 (2023): June
You may also start an advanced similarity search for this article.