Estimated Glomerular Filtration Rate (eGFR) as a Predictor of 1-Month Clinical Outcome in First-Ever Acute Ischemic Stroke Patients
Authors
Abstract
Introduction: Renal dysfunction is a new risk factor that is thought to influence the clinical outcome of acute ischemic stroke. In this case, the estimated glomerular filtration rate (eGFR) value is used as an approach to assess kidney function status in acute ischemic stroke patients. This study aims to find the relationship between eGFR and clinical outcomes of acute ischemic stroke.
Method: 70 samples were obtained according to inclusion criteria. eGFR is calculated within first week of stroke onset using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula. A normality test was carried out on the data, then determined the correlation and compared eGFR with good [modified Rankin Scale (mRS) 0-2] and poor (mRS 3-6) clinical outcomes on the 30th day.
Results: In this study, the average age of the sample was 61.37 years. The largest population was in the 45-59 mL/min/1.73 m2 eGFR group (38,6%). The mean eGFR (p<0.001) for all samples, good, and bad outcome groups was respectively 59.90 ± 21.09, 79.79 ± 19.21, and 52.49 ± 16.57. In this study the poor outcome group had a lower mean eGFR than the good outcome group (52.49 mL/min/1.73 m2 vs 79.79 mL/min/1.73 m2), with a cut-off value of 62 mL/min/1.73 m2 (sensitivity 80.39%, specificity 84.21%) tended to have worse clinical outcomes.
Conclusion: Based on the results of this study, eGFR has a relationship with clinical outcomes (p<0.001) and can objectively predict clinical outcomes on the 30th day of acute ischemic stroke.
Similar Articles
- Ratna Mariana Tamba, Hilfan Ade Putra Lubis, Zulfikri Mukhtar, Andika Sitepu, Faisal Habib, Cut Aryfa Andra, T. Bob Haykal, The Relationship between Transient Ischemic Dilation (TID) and Severity of Coronary Artery Disease (CAD) in Patients with Chronic Coronary Syndrome (CCS) in Haji Adam Malik Medan, Indonesia , Journal of Society Medicine: Vol. 2 No. 9 (2023): September
- Diko Hamonangan Saragih, Cut Aria Arina, Iskandar Nasution, The Association Between ASPECTS Score and Dysphagia in Acute Ischemic Stroke Patients , Journal of Society Medicine: Vol. 2 No. 7 (2023): July
- Junius F. A. Simarmata, Kiking Ritarwan, Rabies Encephalitis: Fatal Yet Neglected, A Case Report , Journal of Society Medicine: Vol. 3 No. 2 (2024): February
- Rizka Farahin Assania, Elvita Rahmi Daulay, Refli Hasan, Association of Risk Factors for Coronary Artery Disease with The Incidence of Abdominal Aortic Calcification On Abdominal CT-Scan Imaging in H. Adam Malik General Hospital , Journal of Society Medicine: Vol. 2 No. 3 (2023): March
- Rahmah Evelin Lubis, Diza Tanzira, Nurhakiki Zahara Arif, Cardiovascular Disease with COVID-19 in Rural Area: Case Series , Journal of Society Medicine: Vol. 2 No. 6 (2023): June
- Elsha Sinulingga Elsha, Jelita Siregar, Taufik Sungkar, Differences in MPV (Mean Platelet Volume) / Lymphocytes Ratio In Chronic Hepatitis B with and without Cirrhosis Hepatic , Journal of Society Medicine: Vol. 3 No. 6 (2024): June
- Mohammed Habib, Rosuvastatin Plus N Acetylcysteine to Prevention of Contrast Induced Acute Kidney Injury in Patients with Low Mehran Risk Score , Journal of Society Medicine: Vol. 3 No. 6 (2024): June
- Mirton, Pasihulilzan, Hesty Rhauda Ashan, Performed Laparoscopic Surgery For Gastric Perforation: Case Report , Journal of Society Medicine: Vol. 3 No. 6 (2024): June
- Batian Lubis, Dis Bima P Purwaamidjaja, Mayang Indah Lestari, Faisal, Muhammad Husni Thamrin, Febri Akhmad Belinda, A Case Series of Bleeding Complication Post Percutaneous Dilatational Tracheostomy and Management , Journal of Society Medicine: Vol. 2 No. 12 (2023): December
- Robert Sihombing, Osmond Muftilov Pison, Management of Patients with Guillain Barre Syndrome Accompanied by Ventilator Associated Pneumonia , Journal of Society Medicine: Vol. 3 No. 5 (2024): May
You may also start an advanced similarity search for this article.