The Relationship between LDL/ HDL Ratio and Coronary Lesion Severity Measured by Syntax Score in Patients with Non-Elevation Acute Myocardial Infarction at Hajj Adam Malik General Hospital, Medan

T. Rifqi Hashmi; Harris Hasan; Hilfan Ade Putra Lubis

doi:10.47353/jsocmed.v3i5.146

The Relationship between LDL/ HDL Ratio and Coronary Lesion Severity Measured by Syntax Score in Patients with Non-Elevation Acute Myocardial Infarction at Hajj Adam Malik General Hospital, Medan

T. Rifqi Hashmi
Resident of Department of Cardiology, Faculty of Medicine, University of North Sumatra, Medan, Indonesia
Harris Hasan
Staff of Department of Cardiology, Faculty of Medicine, University of North Sumatra, Medan, Indonesia
Hilfan Ade Putra Lubis
Staff of Department of Cardiology, Faculty of Medicine, University of North Sumatra, Medan, Indonesia

Abstract

Introduction: Coronary artery disease (CAD), results from reduced myocardial perfusion leading to angina, myocardial infarction (MI), and/or heart failure. It accounts for one third to one half of cardiovascular cases. A higher SYNTAX score indicates a more complex condition and poorer prognosis in patients undergoing coronary revascularization especially with PCI. This study aims to determine how the LDL/HDL ratio relates to the complexity of coronary lesions (Syntax Score) in coronary heart disease based on characteristics.

Methods: The type of this study was observational analytic retrospective with a cross sectional design. The study was conducted using secondary data through medical record data of patients diagnosed with NSTEMI.

Results: The subjects were 60 people with an average age of 58,1±8,629. It was found that the mean value of the LDL/HDL ratio was 3,95±3,837, in patients with an LDL/HDL ratio ≥ 2.517 it was found that there were 40 sample(66.7%) of whom had a lesion severity level of Syntax score ≥23 ,27 samples (45%), and in patients with an LDL/HDL ratio < 2.517, 20 samples (33.3%) were found to have a lesion severity level of Syntax score ≥ 23 with 4 samples (6.7%).

Conclusion: There is a relationship between the LDL/HDL ratio and the severity of CAD based on the Syntax score with LDL/HDL ratio values being higher in patients with moderate-severe CAD than in patients with mild CAD.

Similar Articles

Aziz Achmad, Zainal Safri, Teuku Bob Haykal, Abdullah Afif Siregar, Nizam Zikri Akbar, Tengku Winda Ardini, Cut Aryfa Andra, Anggia Chairuddin Lubis, Relationship Between Neutrophil-Lymphocyte Ratio Value And Severity of Mitral Stenosis Due to Rheumatic Heart Disease in Outpatients at H. Adam Malik General Hospital Medan , Journal of Society Medicine: Vol. 3 No. 12 (2024): December
Dian Primadia Putri, Rahmad Isnanta Sembiring, Tambar Kembaren, Putri Eyanoer, Relationship of D-dimer Value to Mortality in Covid-19 Patients with Acute Coronary Syndrome at Haji Adam Malik Hospital Medan , Journal of Society Medicine: Vol. 2 No. 4 (2023): April
Har Rawishwar Singh Dhilion, Ali Nafiah Nasution, Andika Sitepu, Association between Systemic Inflammatory Immunity Index and Intracoronary Thrombus Burden in Acute Myocardial Infarction with ST Segment Elevation (IMA EST) Patients Undergoing Primary Percutaneous Coronary Intervention at Haji Adam Malik Hospital , Journal of Society Medicine: Vol. 3 No. 2 (2024): February
Defriyan Ramzi, Refli Hasan, Zainal Safri, Relationship between Atherogenic Index of Plasma (AIP) and Mayor Cardiovascular Event (MACE) in Patients with Acute Myocardial Infarction (IMA) with Percutaneous Coronary Intervention (PCI) in Haji Adam Malik Hospital , Journal of Society Medicine: Vol. 3 No. 5 (2024): May
Maulana Taufik, Dadik Wahyu Wijaya, Andriamuri Primaputra Lubis, The Relationship Between The Characteristics of COVID-19 Patients To Predict Mortality in The COVID-19 ICU Special Care , Journal of Society Medicine: Vol. 1 No. 1 (2022): October
Siti Hasnita Oktavia Purba, Iskandar Nasution, R.A. Dwi Pujiastuti, The Correlation between Dehydration and Early Neurological Deterioration in Acute Hemorrhagic Stroke , Journal of Society Medicine: Vol. 3 No. 1 (2024): January
Marisa Heidiyana, Khairul Putra Surbakti, Haflin Soraya Hutagalung, The Association Between Degree of Severity and Number of Medications with Quality of Life in Parkinson's Disease Patients , Journal of Society Medicine: Vol. 2 No. 4 (2023): April
Fadli Ilhami, Ali Nafiah Nasution, Cut Aryfa Andra, Prognostic Value of Tricuspid Annular Plane Systolic Excursion (TAPSE), Right Ventricular Fractional Area Changes (RV FAC) and Pulses Tissue Doppler S' Wave (PTD S') at 30 Days after Care of Acute Miocardial Infarction Patients in Haji Adam Malik Hospital , Journal of Society Medicine: Vol. 2 No. 5 (2023): May
Clarisa Monica, Taufik Sungkar, Ilhamd, Correlation between Helicobacter Pylori Caga Antibody Serum and Gastric Premalignant Lesions in Helicobacter Pylori Patients , Journal of Society Medicine: Vol. 2 No. 10 (2023): October
Avie Hanindya Dwiyanti Rambe, Chairil Amin Batubara, Correlation between Serum Fibrinogen Level and Acute Ischemic Stroke Severity , Journal of Society Medicine: Vol. 2 No. 8 (2023): August

<< < 1 2 3 4 5 6 > >>

You may also start an advanced similarity search for this article.

PDF

Published at

31. May 2024
https://doi.org/10.47353/jsocmed.v3i5.146
Issue:

Vol. 3 No. 5 (2024): May
Section:

Articles
Keywords:

Myocardial infarction LDL/HDL ratio SYNTAX score CAD
References:

WHO. Cardiovascular Disease (CVDs) fact sheets. World Health Organization. Geneva. 2021.

Vaduganathan M, Mensah G, Turco J, et al. The Global Burden of Cardiovascular Diseases and Risk. J Am Coll Cardiol. 2022; 80 (25): 2361–2371.

Badan Penelitian dan Pengembangan Kesehatan RI. Riset Kesehatan Dasar (RISKESDAS) 2018. Laporan Nasional. 2018: 146-153.

Shin HR, Song S, Cho JA, Ly SY. Atherogenic Index Of Plasma And Its Association With Risk Factors Of Coronary Artery Disease And Nutrient Intake In Korean Adult Men: The 2013–2014 KNHANES. Nutrients 2022; 14 (1071): 1

Tabei SM, Senemar S, Saffari B, Ahmadi Z, Haqparast S. Non-modifiable Factors of Coronary Artery Stenosis in Late Onset Patients with Coronary Artery Disease in Southern Iranian Population. J Cardiovasc Thorac Res. 2014; 6 (1): 51-5.

Sianos, Georgios, Morel, Maximo, Kappetein, Arie. et al. The SYNTAX Score: An Angiographic Tool Grading The Complexity Of Coronary Artery Disease. Euro Intervention Journal of Euro PCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. 2005; 1: 219-27.

Zhang R, Fan Y, Xue Y, Feng Y, Dong C, Wang Y. et al. The LDL/HDL ratio predicts long-term risk of coronary revascularization in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention: a cohort study. Braz J Med Biol Res. 2022; 1: 1.

Burke AP. Pathology of Acute Myocardial Infarction. Department of Pathology. University of Maryland School of Medicine. Department of Cardiovascular Pathology. 2021: 1:1.

Sianos, Georgios, Morel, Maximo, Kappetein, Arie. et al. The SYNTAX Score: An angiographic tool grading the complexity of coronary artery disease. Euro Intervention Journal of Euro PCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. 2005; 1: 219-27

Knuuti J, Wijns W, Saraste A, Capodanno D, Barbato E, Funck-Brentano C, et al. ESC Scientific Document Group, 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes: The Task Force for the diagnosis and management of chronic coronary syndromes of the European Society of Cardiology (ESC). European Heart Journal. 2019; 41 (3): 407–477.

Visseren FLJ, Mach F, Smulders YM, Carballo D, Koskinas KC, Bäck M, et al. ESC Guidelines on cardiovascular disease prevention in clinical practice: Developed by the Task Force for cardiovascular disease prevention in clinical practice with representatives of the European Society of Cardiology and 12 medical societies With the special contribution of the European Association of Preventive Cardiology (EAPC), European Heart Journal. 2021; 42 (34): 3227–3337

Rhee JW, Sabatine MS, Lilly LS. Acute coronary syndrome. In: Lilly LS (ed.) Pathophysiology of Heart Disease: A Collaborative Project of Medical Students and Faculty, 5th edition. Baltimore: Lippincott of Williams and Wilkin. 2015: 166-176.

Gao P, Wen X, Ou Q, Zhang J. Which one of LDL-C /HDL-C ratio and non-HDL-C can better predict the severity of coronary artery disease in STEMI patients. BMC Cardiovasc Disord. 2022; 22 (1): 318

Lippi U, Cappelletti P, Signori D, Burelli C. Clinical chemical indexes and severity of coronary atherosclerosis. Clinica Chimica Acta. 1983; 130 (3): 283–9.

Chen QJ, Lai HM, Chen BD, Li XM, Zhai H, He CH, et al. Appropriate LDL-C-to-HDL-C Ratio Cutoffs for Categorization of Cardiovascular Disease Risk Factors among Uygur Adults in Xinjiang, China. Int J Environ Res Public Health. 2016; 13 (2): 235.

Katakami N, Kaneto H, Osonoi T, Saitou M, Takahara M, Sakamoto F, et al. Usefulness of lipoprotein ratios in assessing carotid atherosclerosis in Japanese type 2 diabetic patients. Atherosclerosis. 2011; 214 (2): 442–7

Zhang S, Zhao Y, Li X, Dai W. The LDL-C/HDL-C ratio and 4-year risk of coronary artery disease: a retrospective study. Europe PMC. 2020; 1–20.

Xu W, Guan H, Gao D, Wang Z, Ba Y, Yang H, et al. The Association of Syntax Score with Levels of Lipoprotein(a) and Inflammatory Biomarkers in Patients with Stable Coronary Artery Disease and Different Low-Density Lipoprotein Cholesterol Levels. Diabetes Metab Syndr Obes. 2020; 13:4297-310.
Share:

Z

Hashmi, T. R., Hasan, H., & Lubis, H. A. P. (2024). The Relationship between LDL/ HDL Ratio and Coronary Lesion Severity Measured by Syntax Score in Patients with Non-Elevation Acute Myocardial Infarction at Hajj Adam Malik General Hospital, Medan. Journal of Society Medicine, 3(5), 154–160. https://doi.org/10.47353/jsocmed.v3i5.146