Antisialogogue Effect of Atropine Sulfate at Dosages of 0.25 Mg and 0.5 Mg Under General Anesthesia with Ketamin
Authors
Abstract
Introduction: Excessive saliva production can becomes an airway problem in conditions of decreased consciousness where there is impaired swallowing function. It increases the risk of aspiration of saliva into the airways that can result in choking. The use of premedication drugs to reduce the incidence of drug-induced hypersalivation can be done as a prevention. The anticholinergic drug class is the drug of choice for the management of hypersalivation in general anesthesia patients who have been given ketamine and ether. Ketamine as a sedating agent will provide a side effect of hypersalivation, where hypersalivation can cause laryngospasm or aspiration, as a form of prevention, anticholinergic drugs such as atropine can be given. The aim of this research was to compare the effect of antisialagogue on the administration of atropine sulfate at a dose of 0.25 mg and 0.5 mg in intravenous general anesthesia patients without ETT with ketamine at Haji Adam Malik General Hospital Medan and Putri Hijau Hospital Medan.
Method: This study used a double blind RCT design. A total of 60 patients with intravenous general anesthesia without ETT with ketamine (1-2 mg/kg BW) were divided into 2 groups of Atropine Sulfas doses (0.25 and 0.5 mg) then the total salivary volume of each patient was measured and analyzed.
Results: There was a significant difference between the treatment groups of 0.25 mg and 0.5 mg in the volume of saliva that had been collected (P-value = 0.008).
Conclusion: There was a significant comparison between the use of 0.25 mg and 0.5 mg atropine in patients at Haji Adam Malik Hospital and Putri Hijau Hospital Medan.
Similar Articles
- Rizka Farahin Assania, Elvita Rahmi Daulay, Refli Hasan, Association of Risk Factors for Coronary Artery Disease with The Incidence of Abdominal Aortic Calcification On Abdominal CT-Scan Imaging in H. Adam Malik General Hospital , Journal of Society Medicine: Vol. 2 No. 3 (2023): March
- Sharanjit Dhillon, Aida Fithrie, Chairil Amin Batubara, The Association between Waist Hip Ratio and Severity of Diabetic Peripheral Neuropaty in Diabetes Melitus Type 2 by Using Toronto Clinical Scoring System , Journal of Society Medicine: Vol. 2 No. 4 (2023): April
- Fariz Nugraha Akbar, Elvita Rahmi Daulay, Taufik Sungkar, Correlation of Fatty Liver Imaging on Abdominal CT-Scan with Dyslipidemia in Haji Adam Malik General Hospital in 2020 , Journal of Society Medicine: Vol. 2 No. 5 (2023): May
- Muhammad Avicienna Zamzami, Elvita Rahmi Daulay, Suzy Indharty, Evan’s Index Values and Its Relationship with Individual Characteristics (Age and Gender) in Head CT-Scan Examination at Haji Adam Malik Hospital Medan 2021-2022 , Journal of Society Medicine: Vol. 2 No. 7 (2023): July
- Rendi Sidiq, Bastian Lubis, Yutu Solihat, Comparison of Pre-Loading Fluid With Norepinephrine Toward Mean Arterial Pressure (MAP) In Sepsis Patients In Intensive Care Unit (ICU) of Haji Adam Malik General Hospital, Medan , Journal of Society Medicine: Vol. 1 No. 2 (2022): November
- Dwi Prianto, Wika Hanida Lubis, Alwi Thamrin Nasution, Correlation Between Depression Level and Red Blood Cell Distribution Width (RDW) and Erythrocyte Sedimentation Rate (ESR) in Chronic Kidney Disease (CKD) Patients Undergoing Regular Hemodialysis at Haji Adam Malik General Hospital Medan , Journal of Society Medicine: Vol. 2 No. 5 (2023): May
- Tasrif Hamdi, What is the function of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in pain processes? , Journal of Society Medicine: Vol. 2 No. 2 (2023): February
- Hendra Wahyudi, Diagnosis of Tuberculosis infection in HIV: A Review , Journal of Society Medicine: Vol. 2 No. 2 (2023): February
- Aulia Iqbal, Dadik Wahyu Wijaya, Bastian Lubis, Perioperative Nutritional Status of Digestive Surgery Laparotomy Surgery , Journal of Society Medicine: Vol. 1 No. 3 (2022): December
- Tasrif Hamdi, Transversus Abdominis Plane (TAP) Steroid Block for Chronic Abdominal Pain Caused by Chronic Postoperative Pain , Journal of Society Medicine: Vol. 2 No. 1 (2023): January
You may also start an advanced similarity search for this article.