Antisialogogue Effect of Atropine Sulfate at Dosages of 0.25 Mg and 0.5 Mg Under General Anesthesia with Ketamin
Authors
Abstract
Introduction: Excessive saliva production can becomes an airway problem in conditions of decreased consciousness where there is impaired swallowing function. It increases the risk of aspiration of saliva into the airways that can result in choking. The use of premedication drugs to reduce the incidence of drug-induced hypersalivation can be done as a prevention. The anticholinergic drug class is the drug of choice for the management of hypersalivation in general anesthesia patients who have been given ketamine and ether. Ketamine as a sedating agent will provide a side effect of hypersalivation, where hypersalivation can cause laryngospasm or aspiration, as a form of prevention, anticholinergic drugs such as atropine can be given. The aim of this research was to compare the effect of antisialagogue on the administration of atropine sulfate at a dose of 0.25 mg and 0.5 mg in intravenous general anesthesia patients without ETT with ketamine at Haji Adam Malik General Hospital Medan and Putri Hijau Hospital Medan.
Method: This study used a double blind RCT design. A total of 60 patients with intravenous general anesthesia without ETT with ketamine (1-2 mg/kg BW) were divided into 2 groups of Atropine Sulfas doses (0.25 and 0.5 mg) then the total salivary volume of each patient was measured and analyzed.
Results: There was a significant difference between the treatment groups of 0.25 mg and 0.5 mg in the volume of saliva that had been collected (P-value = 0.008).
Conclusion: There was a significant comparison between the use of 0.25 mg and 0.5 mg atropine in patients at Haji Adam Malik Hospital and Putri Hijau Hospital Medan.
Similar Articles
- Bramantyo Pamugar, Dhany Budipratama, Lung Protective Strategy in Acute Respiratory Distress Syndrome with Approach of Compliance and Mechanical Power , Journal of Society Medicine: Vol. 2 No. 10 (2023): October
- Fadli Ilhami, Ali Nafiah Nasution, Cut Aryfa Andra, Prognostic Value of Tricuspid Annular Plane Systolic Excursion (TAPSE), Right Ventricular Fractional Area Changes (RV FAC) and Pulses Tissue Doppler S' Wave (PTD S') at 30 Days after Care of Acute Miocardial Infarction Patients in Haji Adam Malik Hospital , Journal of Society Medicine: Vol. 2 No. 5 (2023): May
- Lastri Hillary, Ali Nafiah Nasution, Anggia Chairuddin Lubis, Correlation of P Wave Dispersion and Quality of Life of Heart Failure Due to Coronary Heart Disease Patient in Haji Adam Malik General Hospital , Journal of Society Medicine: Vol. 3 No. 4 (2024): April
- Ridho Kurnia Indra, Andre Pasha Ketaren, Hilfan Ade Putra, Correlation Between Pursuit Score And Severity Of Coronary Artery Lesion Assessed by Syntax Score Among Non-ST-Segment Elevation Myocardial Infarction (NSTEMI) Patients in Adam Malik Hospital Medan , Journal of Society Medicine: Vol. 2 No. 8 (2023): August
- Marisa Heidiyana, Khairul Putra Surbakti, Haflin Soraya Hutagalung, The Association Between Degree of Severity and Number of Medications with Quality of Life in Parkinson's Disease Patients , Journal of Society Medicine: Vol. 2 No. 4 (2023): April
- Astry Amelia Harahap, Alwi Thamrin Nasution, Rahmat Isnanta, The Relationship Between Serum Ferritin Levels and Left Ventricular Function in Patients Undergoing Hemodialysis , Journal of Society Medicine: Vol. 2 No. 10 (2023): October
- Annisa Nidya Rahmatika Sitepu, Dharma Lindarto, Melati Silvanni Nasution, Lipid Profile in Confirmed Covid-19 Patients with Type 2 Diabetes Mellitus At Haji Adam Malik General Hospital Medan from March 2020 to December 2021 , Journal of Society Medicine: Vol. 2 No. 3 (2023): March
- Adi Retno, Evo Elidar Harahap, Bayu Rusfandi Nasution, Relationship between Stage of Chronic Kidney Disease with Cardiomegaly Imaging in Posteroanterior Chest X-Ray at Haji Adam Malik Hospital Medan , Journal of Society Medicine: Vol. 2 No. 8 (2023): August
- Natassya Sandra Tillasman, Putu Pradnyasanti Laksmi, Ratna Rayeni Natasha Roosseno, Agus Roy Rusly Hariantana Hamid, Literature Review for Iliaca, Scapula, and Fibula Free Flap as A Modality in Mandibular Ameloblastoma Reconstruction , Journal of Society Medicine: Vol. 3 No. 6 (2024): June
- Rahmah Evelin Lubis, Diza Tanzira, Nurhakiki Zahara Arif, Cardiovascular Disease with COVID-19 in Rural Area: Case Series , Journal of Society Medicine: Vol. 2 No. 6 (2023): June
You may also start an advanced similarity search for this article.