Blood Eosinophil Count as a Predictor of Asthma Exacerbation
Authors
Abstract
Introduction: Asthma is a heterogeneous disease characterized by chronic airway inflammation, where eosinophils play a crucial role. Eosinophil levels are often considered a biomarker for asthma severity and treatment response. However, their relationship with asthma exacerbation severity remains unclear. This study aimed to evaluate the relationship between blood eosinophil levels and the severity of asthma exacerbations in patients at Prof. Dr. Chairuddin P. Lubis USU Hospital.
Method: This study employed an analytic observational design with a retrospective cohort approach. Data were collected from 25 asthma patients through medical records, including demographic characteristics, blood eosinophil levels, and asthma exacerbation severity. The relationship between eosinophil levels and exacerbation severity was analyzed using the Whitney test.
Results: The majority of asthma patients were in the 26-50 age group (44%) and predominantly female (80%). Most patients had blood eosinophil levels <100 (84%), and severe exacerbations were the most common (72%). Statistical analysis showed no significant relationship between blood eosinophil levels and asthma exacerbation severity (p = 0.976).
Conclusion: This study found no significant correlation between blood eosinophil levels and asthma exacerbation severity. Other factors, such as corticosteroid use, delayed immune response, and non-eosinophilic asthma, may influence exacerbation severity. These findings emphasize the importance of a multidimensional evaluation in asthma management, including the identification of different asthma phenotypes to guide more precise treatment strategies.
Similar Articles
- Rizki Amaliah Damanik, Andika Pradana, Pandiaman Pandia, Analysis of Blood Eosinophil Levels as an Indicator of Controlled Asthma Classification at the University of Sumatra Utara Hospital , Journal of Society Medicine: Vol. 4 No. 3 (2025): March
- Olivia Monica Deneuve, Andika Pradana, Amira P. Tarigan, The Relationship of Blood Eosinophils Levels with Degree of Exacerbation in COPD Patient at Usu General Hospital , Journal of Society Medicine: Vol. 3 No. 7 (2024): July
- Nengah Darmawan, Amira Permatasari Tarigan, Andika Pradana, Relationship Between Asthma Therapy Types, Pulmonary Function, and Asthma Control in Primary Healthcare Facilities in Medan , Journal of Society Medicine: Vol. 4 No. 2 (2025): February
- Olivia Monica Deneuve, Andika Pradana, Amira P Tarigan, The Relationship Between ICS LABA Administration and Blood Eosinophil Levels in COPD Patient at USU General Hospital , Journal of Society Medicine: Vol. 3 No. 12 (2024): December
- Sri Bayani, Amira Permatasari Tarigan, Pandiaman Pandia, Rina Amelia, Budi Jefri, The Effect of Providing Education on the Use of Inhalers on Asthma Degrees Based on the Asthma Control Test (ACT) in Patients at Tanjungpura Hospital , Journal of Society Medicine: Vol. 3 No. 10 (2024): Oktober
- M Yusuf Adira Putra, Amira Permatasari Tarigan, Andika Pradana, Riska Resti, Adini Arifah Ramadhani, Syafiah Amalina Nasution, A Study of Relationship Between Asthma Control Test, Lung Function, & Hospitalization , Journal of Society Medicine: Vol. 3 No. 12 (2024): December
- Antonius Leonardo Purba, Nizam Zikri Akbar, Yuke Sarastri, The Relationship between Myocardial Strain Using 2D Speckle Tracking Echocardiography and Coronary Lesion Severity Measured by Syntax Score in Patients with Chronic Coronary Syndrome at Haji Adam Malik Hospital , Journal of Society Medicine: Vol. 3 No. 4 (2024): April
- Dwi Prianto, Wika Hanida Lubis, Alwi Thamrin Nasution, Correlation Between Depression Level and Red Blood Cell Distribution Width (RDW) and Erythrocyte Sedimentation Rate (ESR) in Chronic Kidney Disease (CKD) Patients Undergoing Regular Hemodialysis at Haji Adam Malik General Hospital Medan , Journal of Society Medicine: Vol. 2 No. 5 (2023): May
- Elsha Sinulingga Elsha, Jelita Siregar, Taufik Sungkar, Differences in MPV (Mean Platelet Volume) / Lymphocytes Ratio In Chronic Hepatitis B with and without Cirrhosis Hepatic , Journal of Society Medicine: Vol. 3 No. 6 (2024): June
- Tasrif Hamdi, Transversus Abdominis Plane (TAP) Steroid Block for Chronic Abdominal Pain Caused by Chronic Postoperative Pain , Journal of Society Medicine: Vol. 2 No. 1 (2023): January
You may also start an advanced similarity search for this article.