Correlation Between Depression Level and Red Blood Cell Distribution Width (RDW) and Erythrocyte Sedimentation Rate (ESR) in Chronic Kidney Disease (CKD) Patients Undergoing Regular Hemodialysis at Haji Adam Malik General Hospital Medan

Dwi Prianto; Wika Hanida Lubis; Alwi Thamrin Nasution

doi:10.47353/jsocmed.v2i5.49

Correlation Between Depression Level and Red Blood Cell Distribution Width (RDW) and Erythrocyte Sedimentation Rate (ESR) in Chronic Kidney Disease (CKD) Patients Undergoing Regular Hemodialysis at Haji Adam Malik General Hospital Medan

Dwi Prianto
Departement of Internal Medicine, Faculty of Medicine University of North Sumatera
Wika Hanida Lubis
Division of Psychosomatic, Departement of Internal Medicine, Faculty of Medicine University of North Sumatera
Alwi Thamrin Nasution
Division of Nephrology and Hypertension, Departement of Internal Medicine, Faculty of Medicine University of North Sumatera

Abstract

Introduction: Chronic Kidney Disease are related to inflammation and stress levels therefore depression is a predictor that will increase the morbidity and mortality of patients with chronic kidney disease undergoing hemodialysis.

Method: This research is an analytical study with a cross-sectional design which carried out in Januari until February 2023, at Hemodialysis Installation of RSUP. H. Adam Malik. To analyze the correlation between the Depression Level and Red Blood Cell Distribution Width (RDW) and Erythrocyte Sedimentation Rate (ESR), the Pearson correlation test was used if the data was normally distributed. If the data is not normally distributed, Spearman's correlation test is performed. Statistical analysis using 95% confidence level (p<0.05).

Results: In this research, demographic characteristics of 85 patients with mean age of the patients was 49.56 years old with a standard deviation of 13.46. Based on Spearman rho test it was found that there was a significant correlation between RDW and the BDI II score with p value 0.003. The degree of correlation or r value was 0.318. This indicates that there is a weak correlation between the RDW score and the BD II score. Based on Pearson test it was found that there was a significant correlation between ESR and the BDI II score with p value 0.009. The degree of correlation or r value was 0.280. This indicates that there is a weak correlation between the ESR value and the BD II score.

Conclusion: Level of depression were found to be correlated with Red Blood Cell Distribution Width (RDW) and Erythrocyte Sedimentation Rate (ESR) in CKD patients whose undergoing regular hemodialysis.

Similar Articles

Indah Nasution, Karina Sugih Arto, Bugis Mardina Lubis, Correlation between Glycated Hemoglobin and Calcium Levels in Pediatric with Type 1 Diabetes Mellitus , Journal of Society Medicine: Vol. 2 No. 11 (2023): November
Bramantyo Pamugar, Dhany Budipratama, Lung Protective Strategy in Acute Respiratory Distress Syndrome with Approach of Compliance and Mechanical Power , Journal of Society Medicine: Vol. 2 No. 10 (2023): October
Clarisa Monica, Taufik Sungkar, Ilhamd, Correlation between Helicobacter Pylori Caga Antibody Serum and Gastric Premalignant Lesions in Helicobacter Pylori Patients , Journal of Society Medicine: Vol. 2 No. 10 (2023): October
Rezkyana Danil, Nelva Karmila Jusuf, Imam Budi Putra, The Aryl Hydrocarbon Receptor (AhR) Level Based on Age and Clinical Type of Melasma , Journal of Society Medicine: Vol. 3 No. 7 (2024): July

<< < 7 8 9 10 11 12

You may also start an advanced similarity search for this article.

PDF

Published at

31. May 2023
https://doi.org/10.47353/jsocmed.v2i5.49
Issue:

Vol. 2 No. 5 (2023): May
Section:

Articles
Keywords:

Depression Red blood cell distribution width Erythrocyte edimentation rate Chronic kidney disease
References:

Kementerian Kesehatan RI. Infodatin (Pusat Data dan Informasi Kementerian Kesehatan RI). 2018.

Michopoulos V, Powers A, Gillespie C, Ressler K, Jovanovic T. Inflammation in fear and anxiety based disorders : PTSD, GAD, and beyond. Neuropsychopharmacology. 2017; 42(1): 254-270.

Melmed S. and Jameson L. Anterior pituitary : Physiology of pituitary hormones 'In Harrisons Principles of Internal Medicine. New York: McGraw-Hill Education. 2015.

Zahed N, Sharifi M, Karimi M, Nikbakht H. Impact of sertraline on serum concentration of CRP in Hemodialysis patient with depression. Journal of Renal Injury Preventation. 2017; 6(1): 65-6.

Palmer S, Vecchio M, Craig J, Tonelli M, Johnson D, Nicolucci A. et al. Prevalence of depression in chronic kidney disease : Systematic review and meta-analysis of observational studies. Kidney Int. 2013; 84(1): 79-91.

Tekce H, Kin Tekce B, Aktas G, Tanrisev M. and Sit M. The evaluation of red cell distribution width in chronic hemodialysis patients. International journal of nephrology. 2014; 1: 1.

McPherson R. and Pincus M. Henry's Clinical Diagnosis and Management by Laboratory Methods. Elsevier Saunders: London. 2011.

Alsomaili MI, Yousuf M, Hejaili F, Almotairi W, Al-Sayyari AA. Erythrocyte sedimentation rate in stable patients on chronic hemodiaysis. Saudi Journal of Kidney Diseases and Transplantation. 2015; 26(6): 1149.

Demircan F, Gozel N, Kilinc F, Ulu R, Atmaca M. The impact of red blood cell distribution width and neutrophil/lymphocyte ratio on the diagnosis of major depressive disorder. Neurol Ther. 2016; 5: 27-33

Batista-García F, Hernández M, Suria S, Esparza N, Checa MD. Diabetic foot and renal failure. Theoretical and practical considerations. Nefrologia. 2012; 32(3): 399. DOI: https://doi.org/10.3265/Nefrologia.pre2012.Feb.11385

Shafiee M, Tayefi M, Hassanian SM, Ghaneifar Z, Parizadeh MR, Avan A. et al. Depression and anxiety symptoms are associated with white blood cell count and red cell distribution width: A sex-stratified analysis in a population-based study. Psychoneuroendocrinology. 2017; 84: 101–108. DOI: https://doi.org/10.1016/j.psyneuen.2017.06.021

Wysokiński A. and Szczepocka E. Red blood cells parameters in patients with acute schizophrenia, unipolar depression and bipolar disorder. Psychiatria Danubina. 2018; 30(3): 323–330. DOI: https://doi.org/10.24869/psyd.2018.323

Feng J, Lu X, Li H, Wang S. High neutrophil-to-lymphocyte ratio is a significant predictor of depressive symptoms in maintenance hemodialysis patients: a cross-sectional study. BMC Psychiatry. 2022; 22(1): 1-8. DOI: https://doi.org/10.1186/s12888-022-03963-7

Lin Z, Lawrence WR, Huang Y, Lin Q, Gao Y. Classifying depression using blood biomarkers: A large population study. Journal of Psychiatric Research. 2021; 140: 364–372. DOI: https://doi.org/10.1016/j.jpsychires.2021.05.070

Setyaningrum RH, Septiawan D, Batong JP. Relationship between Anxiety Score and Erythrocyte Sedimentation Rate (ESR) in Hemodialysis Patient. Indonesian Journal of Medicine. 2020; 5(02): 109-115.

Vargas HO, Nunes SOV, de Castro MRP, Vargas MM, Barbosa DS, Bortolasci CC, Venugopal K, Dodd S, Berk M. Oxidative stress and inflammatory markers are associated with depression and nicotine dependence. Neuroscience Letters. 2013; 544: 136–140. DOI: https://doi.org/10.1016/j.neulet.2013.03.059

Chang CC, Tzeng NS, Kao YC, Yeh CB, Chang HA. The relationships of current suicidal ideation with inflammatory markers and heart rate variability in unmedicated patients with major depressive disorder. Psychiatry Research. 2017; 258: 449–456. DOI: https://doi.org/10.1016/j.psychres.2017.08.076
Share:

Z

Prianto, D., Lubis, W. H., & Nasution, A. T. (2023). Correlation Between Depression Level and Red Blood Cell Distribution Width (RDW) and Erythrocyte Sedimentation Rate (ESR) in Chronic Kidney Disease (CKD) Patients Undergoing Regular Hemodialysis at Haji Adam Malik General Hospital Medan. Journal of Society Medicine, 2(5), 164–169. https://doi.org/10.47353/jsocmed.v2i5.49